Principles of Neural Science-轻识

This title now updated: the definitive neuroscience resource-from Eric R. Kandel, MD (winner of the Nobel Prize in 2000); James H. Schwartz, MD, PhD; Thomas M. Jessell, PhD; Steven A. Siegelbaum, PhD; and A. J. Hudspeth, PhD 900 full-color illustrations. Deciphering the link between the human brain and behavior has always been one of the most intriguing - and often challenging-aspects of scientific endeavor. The sequencing of the human genome, and advances in molecular biology, have illuminated the pathogenesis of many neurological diseases and have propelled our knowledge of how the brain controls behavior. To grasp the wider implications of these developments and gain a fundamental understanding of this dynamic, fast-moving field, Principles of Neuroscience stands alone as the most authoritative and indispensible resource of its kind. In this classic text, prominent researchers in the field expertly survey the entire spectrum of neural science, giving an up-to-date, unparalleled view of the discipline for anyone who studies brain and mind. Here, in one remarkable volume, is the current state of neural science knowledge - ranging from molecules and cells, to anatomic structures and systems, to the senses and cognitive functions-all supported by more than 900 precise, full-color illustrations. In addition to clarifying complex topics, the book also benefits from a cohesive organization, beginning with an insightful overview of the interrelationships between the brain, nervous system, genes, and behavior. Principles of Neural Science then proceeds with an in-depth examination of the molecular and cellular biology of nerve cells, synaptic transmission, and the neural basis of cognition. The remaining sections illuminate how cells, molecules, and systems give us sight, hearing, touch, movement, thought, learning, memories, and emotions. The new fifth edition of Principles of Neural Science is thoroughly updated to reflect the tremendous amount of research, and the very latest clinical perspectives, that have significantly transformed the field within the last decade. Ultimately, Principles of Neural Science affirms that all behavior is an expression of neural activity, and that the future of clinical neurology and psychiatry hinges on the progress of neural science. Far exceeding the scope and scholarship of similar texts, this unmatched guide offers a commanding, scientifically rigorous perspective on the molecular mechanisms of neural function and disease-one that you'll continually rely on to advance your comprehension of brain, mind, and behavior. Features: the cornerstone reference in the field of neuroscience that explains how the nerves, brain, and mind function; clear emphasis on how behavior can be examined through the electrical activity of both individual neurons and systems of nerve cells; current focus on molecular biology as a tool for probing the pathogenesis of many neurological diseases, including muscular dystrophy, Huntington disease, and certain forms of Alzheimer's disease; more than 900 engaging full-color illustrations - including line drawings, radiographs, micrographs, and medical photographs clarify often-complex neuroscience concepts; outstanding section on the development and emergence of behavior, including important coverage of brain damage repair, the sexual differentiation of the nervous system, and the aging brain. Features: more detailed discussions of cognitive and behavioral functions, and an expanded review of cognitive processes; a focus on the increasing importance of computational neural science, which enhances our ability to record the brain's electrical activity and study cognitive processes more directly; and chapter-opening. Key concepts: provides a convenient, study-enhancing introduction to the material covered in each chapter; selected readings and full reference citations at the close of each chapter facilitate further study and research; and helpful appendices highlight basic circuit theory; the neurological examination of the patient; circulation of the brain; the blood-brain barrier, choroid plexus, and cerebrospinal fluid; neural networks; and theoretical approaches to neuroscience.

埃里克 R. 坎德尔（Eric R. Kandel）

2000年诺贝尔生理学或医学奖获得者，是美国著名的哥伦比亚大学生物化学、分子生物物理学、生理学、细胞生物物理学和精神病学教授，是霍华德休斯医学研究所高级研究员，曾被授予美国国家科学勋章。

他于1929年出生于奥地利的维也纳，1956年毕业于美国纽约大学，获医学博士学位，1983年至今任哥伦比亚大学生物化学、分子生物物理学、生理学、细胞生物物理学和精神病学教授、霍华德休斯医学研究中心高级研究员，他也是美国国家科学院的成员。

2000年，坎德尔博士因其对神经系统学领域的开创性贡献与保罗格林加德共同获得诺贝尔生理学和医学奖。值得一提的是，他因在神经细胞记忆存储的生理学基础方面的研究获得这份殊荣。坎德尔博士还获得其他多个奖项，包括美国国家科学勋章、艾伯特拉斯克医学研究奖（Albert Lasker Bas...

埃里克 R. 坎德尔（Eric R. Kandel）

2000年，坎德尔博士因其对神经系统学领域的开创性贡献与保罗格林加德共同获得诺贝尔生理学和医学奖。值得一提的是，他因在神经细胞记忆存储的生理学基础方面的研究获得这份殊荣。坎德尔博士还获得其他多个奖项，包括美国国家科学勋章、艾伯特拉斯克医学研究奖（Albert Lasker Basic Medical Research Award）、盖尔德纳国际医学科学杰出成就奖（Gairdner International Award for Outstanding Achievement in Medical Science）、沃尔夫奖，等等。他还获得18个荣誉学位。

坎德尔博士因主编《神经科学原理》而备受赞誉。他的自传《追寻记忆的痕迹》（In Search of Memory: The Emergence of a New Science of Mind）叙述了他非凡的生活和职业成就，曾荣获《洛杉矶时报》图书奖。他的其他著作包括Cellular Basis of Behavior: An Introduction to Behavioral Neurobiology，Behavioral Biology of Aplysia: A Contribution to the Comparative Study of Opisthobranch Molluscs，Molecular Neurobiology in Neurology and Psychiatry和Memory: From Mind to Molecules（与 Larry R.Squire 合著）。